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Arrows indicate when the investigational product was administrated: at day 1, 29, and 57

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doi: 10.1016/j.eclinm.2025.103464 132 WhartonSFreitasPHjelmesthJKabischMKandlerKLingvayIet al

On the one hand, JEV infection destroyed the antioxidant system in neuronal cells by inhibiting the GSH-GPX4 signaling axis

It does not reverse enamel erosion, but it removes the bacterial environment that accelerates further damage, making it a critical first step in any treatment plan