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In rats with HPA axis suppression, constant infusion of ACTH did not induce pulsatile glucocorticoid secretion (157)

This finding suggests that some of the clinical variation in efficacy and side effects seen in GLP-1 patients stems from a fundamental change in the receptors own biology rather than other complex factors that can affect drug response indirectly

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This guide answers that question using the same compatibility framework we give every patient who starts a multi-peptide protocol at our clinic