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As in HUVEC cell lines, only atorvastatin and lovastatin could cause cell death (Supplementary Figure S1A), but the cell death induced by atorvastatin or lovastatin could not be rescued by ferroptosis inhibitors (Supplementary Figures S1B,C)

Therefore for this group of drugs extraction is influenced by changes in protein binding more than by changes in hepatic blood flow

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Once youre comfortable, a small IV catheter is typically inserted into your arm