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Methylation connects with glutathione through homocysteine and the transsulfuration pathway, which can provide cysteine for glutathione synthesis

Additionally, glutamine contributes to the intermediary metabolism [19] in the synthesis of amino sugars and proteins [20,21,22], promotes insulin secretion from pancreatic beta cells, and is the precursor of key molecules such as the excitatory neurotransmitter glutamate, the inhibitory neurotransmitter -aminobutyrate (GABA), and the antioxidant glutathione (GSH) [1, 23, 24], considered a powerful marker of the cellular redox potential [25, 26]

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Cell Death Differ 10:249256 Lang KS, Lang PA, Bauer C et al (2005) Mechanisms of suicidal erythrocyte death

Sirt2 functions as a histone delactylase and inhibits the proliferation and migration of neuroblastoma cells

doi: 10.1186/1742-9994-10-33 17 BhardwajNKumarAGuptaNJ