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The dosage of AOD9604 used in this study or 0.25 mg per injection, was carefully calculated to be molar equivalent to doses of full-length GH shown to be effective in prior rabbit OA studies

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When the thyroid is hyperactive, it accelerates several bodily activities, resulting in symptoms including tremors, anxiety, fast pulse, excessive perspiration, and weight loss

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity