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[48] [49] [50] [51] [52] [53] [54] Dihydrolipoic acid (DHLA) can also form intracellularly and extracellularly via non-enzymatic, thiol-disulfide exchange reactions

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Red flag symptoms requiring immediate evaluation include fever above 101F, hearing loss, purulent ear drainage, or facial swellingthese suggest serious infection or complications

The most common complaints were nausea (55% versus 12.6% with placebo), constipation (30.7% versus 11.6%), and vomiting (26.1% versus 4.1%)

These oxidative effects can be neutralized by antioxidant systems, engaging in a delicate balance that determines the fate and impact of ROS in cells

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