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That's the copper ion, and it's completely normal
The combination is safe and effective for Fitzpatrick III to V skin when the needle depth and session frequency are calibrated conservatively, and when the patient follows consistent sun protection
In practice, GHK-Cu is often layered with PRP, exosomes, and lasers as part of combination protocols aimed at accelerating recovery and enhancing visible outcomes
Toxicol Vitr
De Groot AC
Ismail Kimji, MD, FRCPC Royal College of Physicians and Surgeons of Canada Published 26 May 2026 34-minute read 10,400 words 18 peer-reviewed sources 42 inline citations Next medical review: November 2026 Eight things to know about microinfusion serum delivery Fact 01 The stratum corneum is 10 to 30 microns thick and blocks any topical molecule larger than 500 Daltons
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