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They may employ a strategy where after a set period (say 3 or 6 months), they assess improvement and consider a drug holiday or taper to ensure that continuing is warranted

doi: 10.1007/s10719-016-9705-z

mSystems 6 , e0104521 (2021)

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(He marketed a T-shirt that read Caffeine is My Drug of Choice through an online news group in 1993.) But by his mid-twenties, his health was out of control