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Instead, we observed that the atorvastatin, fluvastatin, lovastatin, pitavastatin, and simvastatin are lipophilic statins, whereas pravastatin and rosuvastatin are hydrophilic (Figure 2B)

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A375 cells were cultured until 3050% confluence, then treated with a complete growth medium containing 0.1 M doxorubicin (Sigma D1515)