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Choose Reta + MOTS-c when mitochondrial support during the deficit matters more than full GH-axis recomp

Mao, A.S., Shin, J-W., Utech, S., Wang, H., Uzun, O., Li, W., Cooper, M., Hu, Y

But the degree of blood sugar improvement differs substantially

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A large, unblinded randomised comparison (TOSCA.IT) of pioglitazone versus sulphonylurea as add-on to metformin showed similar rates of the composite of MACE endpoint as well as its individual components

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