Recent research highlights the role of specific immune pathway alterations in modifying fungal behaviour, tissue response, and disease distribution
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368 Since GLP-1R is expressed in thyroid C cells and GLP-1 directly stimulates the secretion of calcitonin, which is a potent inhibitor of bone resorption in osteoclasts, GLP-1 may contribute to the nutrient-mediated reduction in bone resorption
& Denamur, E
Therefore, other anti-diabetic agents may be required to meet the therapeutic goals of glycated hemoglobin, which are recommended by several clinical guidelines 15,16
But that day, if it ever comes, is likely many years away