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This allows it to remain active in the bloodstream much longer than the bodys own GLP1, which results in more sustained effects

Weight changes during this period are generally modest as the body adjusts to the medication

Self-administering an unverified version without medical oversight adds a layer of risk

A recent pharmacoepidemiological study found that receipt of GLP-1RAs was associated with reduced Alcohol Use Disorder Identification Test Consumption scores, whereas DPP-4 inhibitors, another class of antidiabetic medications that increase endogenous GLP-1 levels (see Figure 1), had no effect of alcohol intake [70]

doi: 10.1016/j.ejphar.2019.172844 78 HitomiHKiyomotoHNishiyamaA

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