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Standard oral dosing is 500 mcg once daily on an empty stomach

Clinical trial data from the SURMOUNT-1 study showed that gastrointestinal adverse events were significantly more common during dose escalation periods (Jastreboff et al., 2022, NEJM)

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It is a selective agonist of the growth-hormone-secretagogue receptor GHSR-1a, first characterized in peer-reviewed literature by Raun et al

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