"There is not much out there that is clearly that effective." He said, "I would be shocked if this stuff (meldonium) had an effect greater than, say, caffeine or creatinine (a natural substance that, when taken as a supplement, is thought to enhance muscle mass), if any effect at all." Adding meldonium to the prohibited list of performance-enhancing substances could have the opposite of the desired effect, at least among athletic competitors who aren't routinely tested for doping, Joyner said
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