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High concentrations or chronic administration of glucocorticoids promote apoptosis of immune cells, including T cells, macrophages, dendritic cells, and eosinophils in mice and humans (89), whereas lower concentrations and shorter exposure windows exhibit more nuanced effects on inflammation and immunity
Individuals who significantly restrict their caloric intake, whether intentionally or as a result of nausea, are at greater risk of prolonged fatigue due to insufficient macronutrient and micronutrient intake
We identify mitochondrial trifunctional protein- (MTP) as a binding partner of GLP-1(2836) and demonstrate that the ability of GLP-1(2836) to shift substrate utilization from oxygen-consuming fatty acid metabolism toward oxygen-sparing glycolysis and glucose oxidation and to increase cAMP levels is dependent on MTP
Cell Stem Cell 12 , 329341 (2013)
