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doi: 10.1007/s10549-011-1585-0

La mortalidad es 12 a 20%, generalmente debida a la insuficiencia cardaca o por otras complicaciones como la compresin traqueal, infecciones y trombocitopenia

doi:10.1016/j.biotechadv.2011.06.016

To date, over 100 nitrones have been assessed as STs 4,5 and the NIH spin-trapping database contains more than 10,000 entries from experiments performed with approximately 20 STs ( Analysis of EPR spectra and the stability of analogous series of spin-adducts indicates that cyclic STs with an H and a tertiary C atom (Fig

Moreover, LC administrated for 2 weeks suppresses atrogin-1 messenger RNA (mRNA) level in suspended rats hindlimb [35], and only 7 days of LC administration downregulates MuRF-1 and atrogin-1 mRNAs reducing muscle wasting in a rat model of cancer cachexia [32]

References Marty, A