doi: 10.3389/fendo.2022.838410 41 UsdinTBMezeyEButtonDCBrownsteinMJBonnerTI
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It is a triple agonist, meaning it activates GLP-1 (glucagon-like peptide-1), GIP (glucose- dependent insulinotropic polypeptide) and glucagon receptors making it one of the most comprehensive peptide candidates in obesity, insulin resistance and metabolic research
The Evolving Weight-Loss Landscape Over the past few years, incretin-based therapies have reshaped the obesity and type 2 diabetes treatment paradigm