Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors, not yet licensed by the MHRA or EMA, and currently in Phase 2 and Phase 3 clinical trials
2022;7(19):e159863
Amylin signals in the hindbrain (a separate part of the brain from where GLP-1 acts)
Compare their mechanism, effectiveness, side effects, cost, availability, and pros and cons to make an informed choice
Dosing Schedule, Storage, and Handling Instructions Retatrutide is investigated as a once-weekly subcutaneous injection, starting at 2 mg and escalating incrementally to up to 12 mg
FYI, Wegovy has a typical maintenance dosage of 1.7 mg or 2.4 mg weekly