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These effects appear to result from the medications' impact on dopamine pathways and reward-seeking behavior ^10

Side Effects, Tolerability, and Dose Adjustment Nausea is the most frequent side effect during dose escalation, occurring in 2540% of patients in clinical trials

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Dipeptidyl peptidase 4 inhibition for prophylaxis of acute graft-versus-host disease

Group II and group III metabotropic glutamate receptor agonists depress synaptic transmission in the rat spinal cord dorsal horn

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