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The co-occurrence of high NRF2 target genes with low lipogenic genes was shared by some tissues but not all (Fig

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To gain further insight into the different binding sites of Chc, we performed native mass spectrometry (native MS) experiments on Ent5.1 CBM, the strongest binder of the evaluated peptides (Supplementary Fig

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The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS