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At the end of the study, the women had lost an average of 4.4 kg (9.7 lbs) and had significant improvements in insulin resistance, fasting glucose, and cholesterol levels

The 500 Dalton rule for the skin penetration of chemical compounds and drugs

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Reported side effects include water retention, flushing, headache, tingling in the extremities, elevated IGF-1 levels, impaired glucose tolerance, and injection site reactions including pain and infection risk

Allergic reactions to semaglutide include hives, swelling, throat tightness, or difficulty breathingthese require immediate emergency care