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The compound incorporates three non-standard structural features: an -aminoisobutyric acid (Aib) at the N-terminus bearing no stereocenter, a D-2-naphthylalanine (D-2-Nal) at position 3, and a D-phenylalanine at position 4

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For acute injury models, daily dosing is common for the first 7-14 days, transitioning to less frequent administration as the recovery window progresses

Results Across 32 PGICs, we found 13 unique response sets, and 17 recall periods

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(2) Immunological and chemical barriers: Alveolar macrophages, proteolytic enzymes, and surfactants make up the majority of the immunological and chemical barriers found in the lungs