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This study is the fifth in a line of randomised trials its STEP 5, with the first four STEPs being published in 2021 with impressive results

But GLP-1-receptor agonists such as liraglutide reduce cerebrospinal fluid secretion and have already proved effective in treating idiopathic intracranial hypertension (IIH)

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Semaglutide is the most extensively studied GLP-1RA, with multiple trials, including SUSTAIN-6, PIONEER-6, FLOW, and SOUL [20,21,22, 31], collectively establishing a robust evidence base for cardiorenal risk reduction in T2D, with SELECT extending these benefits to adults with overweight/obesity and established ASCVD without diabetes [32]

For those considering tirzepatide or currently using it, having access to reliable medical advice is essential