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Knockout of mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 (mtGPAT1), a major hepatic glycerol-3-phosphate acyltransferase, decreased de novo DAG generation protecting mice from hepatic insulin resistance (195)

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This combination offers additional benefits including: Improved acetylcholine production and protection, a more balanced inflammatory response from powerful antioxidant properties, and support of a healthy lipid profile.