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The highest incidence of nausea and vomiting occurred during dose escalation phases

Initially used to treat rheumatoid arthritis and multiple sclerosis, DHODH inhibitors were later found helpful in treating cancer, viral infections, and blood disorders [55,56,57,58]

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Available from: Sears ME

Clinical evaluation: Patient history: symptoms such as weight changes, energy levels, temperature sensitivity, and emotional well-being can provide clues

Assembly of RNA polymerase II transcription initiation complexes