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The biologic effects of IGFs signaling on cancer Once activated by the ligands, IGF-IR and InsR may initiate diverse signaling pathways to regulate cell proliferation, differentiation, survival, metabolism, migration, and stemness (Fig

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Vitamin B12 is necessary for the production of red blood cells, which help carry oxygen throughout the body

They are capable of encapsulating both hydrophilic and lipophilic drugs, exhibit good cell affinity and histocompatibility, and can improve drug stability 24,25

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