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Whether or not that framing fully resolves the regulatory picture, it is the lens he uses for everything that follows

10.3390/genes9070314 50 GuoY.-J.PanW.-W.LiuS.-B.ShenZ.-F.XuY.HuL.-L

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Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, Douglas IS, Pearse DB, Tuder RM