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Semaglutide vs Traditional Weight Loss Drugs Older weight loss medications like phentermine, orlistat, or naltrexone-bupropion produce much more modest resultstypically 5-10% weight loss compared to semaglutides 12-15%

Weight Loss Results: Clinical Data on Phentermine vs Semaglutide Phentermine typically produces weight loss of 3 to 7 pounds per month during short-term use, with average total losses ranging from 10 to 20 pounds over a 12-week course

These include improved outcomes in people with cardiovascular, kidney, liver, arthritis, sleep apnea, and substance abuse disorders, along with reducing inflammation generally

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But walking does not create the mechanical load that forces your muscles to adapt and grow