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This precision approach reduces trial-and-error dosing, accelerates symptom relief, and improves long-term adherence

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ABHD11 acts as a glutaryllipoyl thioesterase The most likely explanation for increased Lp glu following ML226 treatment was that the serine hydrolase activity of ABHD11 regulated the lipoyl adduct

doi: 10.1038/s41598-021-97967-0 195 InaishiJSaishoY