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Topical maintenance is likely necessary regardless of initial delivery method, since the skin continuously turns over collagen

(2) topics presented outside the scope of the review

Additionally, both GLP-1 and GIP play a role in cardiovascular disease, as agonists of GLP-1 have been shown to reduce platelet activation, thus supporting a protective effect of GLP-1 against microvascular thrombosis [24]

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When PCPs Refer to Specialists and Safety Monitoring Protocols PCPs manage many GLP-1 patients independently, but referral to endocrinologists, cardiologists, or obesity medicine specialists is appropriate for complex cases: severe renal impairment, active cardiovascular disease, concurrent use of insulin, or inadequate response to initial dosing