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Fact: They serve different primary roles

With advancements in materials science, targeted delivery of iron ions to bacteria to enhance oxidative stress enables specific bacterial elimination, while adjusting material components can protect host cells from ferroptosis [98, 99]

DOI: 10.1016/j.chemphyslip.2017.08.001

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In conclusion, while addressing vitamin B12 deficiency is important, a holistic approach to treating melasma involves lifestyle changes and topical treatments