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PNPLA3-I148M variant promotes the progression of liver fibrosis by inducing mitochondrial dysfunction

Besides mitochondria, several other cellular organelles likely endoplasmic reticulum (ER), peroxisomes, plasma membrane, cytosol and nucleus with high oxygen consumption serve as endogenous sources to form ROS

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These two tools, used together, eliminate the most common source of error in peptide research: hand-math gone wrong at 2 a.m

10.1016/S0954-6111(03)00026-X 80 GronebergD

Research has documented lower circulating MOTS-c in patients with obesity, type 2 diabetes, and insulin resistance, and higher levels in populations with healthy metabolic aging