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Higher baseline deficiency risk in the target population Research has consistently shown that individuals with obesity have higher rates of B12 deficiency compared to the general population

41 A 1-year follow up on 72 of these subjects found that those who stayed on micronutrients still had significant improvement over the initial baseline and performed better than those who had switched to psychiatric medications or discontinued micronutrient treatment

Some patients move slower if side effects make escalation difficult at certain phases

Mita M, Sankhala K, Abdel-Karim I, Mita A, Giles F

Psychiatry 8:66

The word stroke is used because, as with the more familiar condition, the underlying cause is a loss of blood supply that leads to cell death and tissue damage