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GLP-1 RAs don't suppress insulin secretion or alter ketone metabolism in the same way, making their safety profile meaningfully different

Hunter Guevara LR, Beam WBB, Pasternak JJ (2024) To the Brain and Beyond: Neurological Implications of Glucagon-Like Peptide-1 Receptor Agonists

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The same study also reported fewer cases of respiratory failure, pneumonia, substance use disorders, and seizures

4 Others: GIPR/GLP-1R dual agonists and GIPR/GLP-1R/GCGR triagonists Intestinal endocrine K cells produce gastric inhibitory polypeptide (GIP)

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