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Some patients used compounded tirzepatide because they could not afford branded medicine

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In head-to-head trials (SURMOUNT-5), tirzepatide produced greater weight loss than semaglutide

Clinical Implications for GLP-1Based Therapies The findings raise important considerations for the use of GLP-1 receptor agonists, widely prescribed for diabetes and obesity, in individuals predisposed to neuroinflammatory conditions