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This approach could enable initial treatment with highly effective but expensive GLP-1 agonists, followed by maintenance with more affordable alternatives

Rybelsus : oral administration (once daily) semaglutide has been co-formulated with salcaprozate sodium (SNAC), a small fatty acid derivative that acts as an absorption enhancer that provides a unique, site-directed tablet release with absorption of semaglutide in the stomach when administered orally

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Together, these effects may lead to weight loss and reductions in body fat

Patients with a personal or family history of medullary thyroid carcinoma should avoid GLP-1 agonists

The combination may be used to help with blood sugar control, weight loss, or both