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PMID: 23121085

The absolute dosing regardless of body mass likely increased the variability of response within supplementation groups thereby limiting the findings of the present study

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18 BLM induced the upregulation of Col12, Col31 and Col4a2 mRNA expression compared with control, and FOXO4DRI repressed BLMinduced upregulation of the above genes similar to PFD group (Figure 1E)

Some may notice changes sooner, while others may see more gradual effects over time

Deviating from this schedule has not been systematically studied, making provider guidance essential before making any changes