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Selective and membrane-permeable small molecule inhibitors of Nicotinamide N-Methyltransferase reverse high fat diet-induced obesity in mice

- Increased Energy Levels: Converts stored fat into energy, boosting stamina for workouts and daily activities

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Last reviewed: July 18, 2026 Last updated: July 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Choline deficiency can lead to fatty liver accumulation

This review study highlights the biological effects of different NAD+ boosters as well as the unique benefits of direct NAD+ administration over oral precursors because it bypasses gut and liver metabolism