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Nevertheless, the data sheets of several GLP-1 RAs do not recommend their administration to patients with severe gastrointestinal disease due to the limited experience in managing this condition

The most likely cause of a withdrawal (If one were to occur) would probably be increased heart-rate caused by the agonisation of GLP1R and GR in particular [56] , [57] , effects that occur in part due to the expression of GLP1R and GR by the heart

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Work focuses on receptor pharmacology and pathway profiling exclusively in controlled, non-clinical in-vitro environments

Scandinavian J Immunol (1994) 40:6018