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"Lipotoxicity in kidney, heart, and skeletal muscle dysfunction." Nutrients 11.7 (2019): 1664

Give each specific spot at least 4-6 weeks before reusing it

Early preclinical studies in experimental diabetes demonstrated toxicities such as anemia, thrombocytopenia, splenomegaly, lymphadenopathy, lung histiocytosis, mortality with multiple organ pathology, gastrointestinal, and central nervous system toxicity

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Overly aggressive dosing could impair recovery if protein and carbohydrate intake are chronically suppressed