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Efficacy and safety of once-weekly tirzepatide in Japanese patients with obesity disease (SURMOUNT-J): A multicentre, randomised, double-blind, placebo-controlled phase 3 trial

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While previous generations GLP-1 agonists (liraglutide) have led to weight loss of 5-10% in most cases, semaglutide can lead to weight loss of up to 20%

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It also helps in reducing free radicals

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However, it's important to check with the manufacturer for any additives or stabilizers used in the injection solution

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Additionally, decreased glycolysis has been observed in CD8+ T cells at rest and after activation (254), CD4+ T cells at rest (254), blood and urine samples (187), and PBMCs (388)

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