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10.1038/cddis.2015.27 100 SongY.LiuJ.ZhaoK.GaoL.ZhaoJ

The evidence tier that is fully published and verifiable is Phase 2

L-arginine fails to protect against myocardial remodelling in L-NAME-induced hypertension

Orlistat causes daily oily stools in 35% of users, which are unavoidable when eating fat

By promoting the use of fat as fuel for muscles, L-Carnitine helps delay muscle glycogen depletion, meaning the body can continue to move more efficiently for longer before it reaches a state of fatigue.