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doi: 10.1016/j.mcna.2012.10.010

Long-term cardiovascular safety wont be confirmed until TRIUMPH-CVOT reports, expected in 2028 at the earliest

However, it should be noted that docking results are only approximations and need to be validated experimentally

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Formulators and analytical chemists should note that the copper-chelated GHK-Cu component imparts a characteristic blue tint upon reconstitution and requires attention to buffer selection, pH range, and avoidance of strong reducing or chelating agents that can perturb the copper coordination sphere