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Although these are promising results, evidence for a protective role for insulin remains low, and a recent Cochrane review from 2017 found no protective or preventive association between cognitive impairment and the use of antidiabetic T2D treatment strategies ( metformin, insulin, repaglinide, glibenclamide, glimepiride, rosiglitazone, gliclazide, perindopril-indapamide )
Another cohort study reported a higher risk of breast cancer in BD patients and their healthy siblings in comparison to the control (Chen et al., 2022), again in line with our thesis of the possible connection between cancer and NDDs
