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Duration varies depending on individual progress, maintenance ability, and long-term weight stability after treatment

Supplementation of autistic children with twice daily administration of 800 g folinic acid and 1000 mg betaine over a 3 month period was effective in normalizing methionine cycle metabolites to the concentrations in controls

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8,9 The effects of SJS continue beyond the healing of the cutaneous lesions to include long-term complications such as vision loss, severe dry eye syndrome, GI/gynecological strictures, and nail disfigurement

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