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Key findings from genetically modeled GLP1R/GIPR agonism: Lower binge-drinking frequency Reduced risk of heavy drinking with psychiatric comorbidities Improved liver health (lower NAFLD & ALT) Cardioprotective effects partially mediated by reduced alcohol use Consistent results across ancestries With AUD treatment access still critically low, these insights highlight a promising new frontier: repurposing metabolic therapies for addiction medicine

Clinical studies show that, with consistent use, patients can experience significant weight loss within a few weeks to months, with some individuals losing up to 15% of their body weight

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The associated risk factors (erectile dysfunction, diabetes mellitus, cigarette smoking, arterial hypertension, and so on) require longer treatment to obtain a good result

C numbers are a current normalized to battery capacity

& Ghafouri, B