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Metsera is developing new GLP-1s, some of which can be taken less often than those currently on the market
Preclinical and clinical studies rigorously examine their anti-inflammatory effects, highlighting significant benefits in these conditions
In animal studies, tirzepatide has been shown to cause thyroid C-cell tumors
13 Two meta-analyses of other GLP-1 RA CVOTs found that GLP-1 RAs were associated with greater rates of DR progression, but both studies found that the effect was driven by the extent of hemoglobin A1c reduction, rather than the medications themselves
Formulations: While most commercial GLP-1 medications are injectables, some compounded versions offer alternative forms like oral capsules, depending on patient preference
LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
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