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1- Weight Loss Results: In a Phase II trial [3], retatrutide achieved up to 24.2% average body weight reduction after 48 weeks of treatment in adults with obesity but without diabetes

Benefits of GLP-1 Drugs GLP-1 drugs are FDA-approved as a treatment for type 2 diabetes and as a weight-loss tool for those with obesity, as they have been demonstrated to be effective treatments for both conditions

Evidence suggests that DPP-4 inhibitors reduce urinary albumin excretion, oxidative stress, and renal dysfunction in patients with T2D independent of their glucose-regulatory activity [117, 118]

Cell 185 , 24782494.e28 (2022)

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