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Transient hunger: Mild and usually manageable

On one side are well-meaning scientists and advocates who feel strongly that powerful and potentially dangerous drugs should be clinically tested in human trials before theyre set loose in the marketplace

By heavily promoting GDNF expression, it reduces brain inflammation, clears out metabolic waste (like the amyloid plaques associated with aging), and revitalizes the dopamine system heavily taxed by modern life, stress, and previous stimulant use

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However, the difference between the short-term and long-term treatments may rather be caused by the aging of the tested mice than by the long-term treatment

Dungan & DeSantis, 2026)