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TMS tris-(hydroxymethyl)-aminomethane the compound was prepared according to the procedure described in Example 1, with the exception that 85.2 mg (0.70 mmol) TRIS was used

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The discrepancy of myricetin between its low oral bioavailability and neuroprotective effects could be coordinated by a metabolism hypothesis: the orally administered myricetin could be converted into a metabolite that penetrates the blood-brain-barrier

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